I’ve written before about grant applications, of courses and of long days in the lab. Nevertheless I have not touched the subject of the emotional rollercoaster involved in doing science.
Especially molecular biology.
So here comes:
The rollercoaster of what we call science
You work hard, long hours. In some ways you work blindly. Relying on faith. Faith to the saneness of your protocols, until you reach the control point. Quite often its many hours, or even days of work until you can get some kind of verification on whether your labours were for nothing or not.
You go through the motions… reach the control point… stare hopefully at the plots and numbers showing up on the machine… Oh no!!! Damn it! Nothing!
”What did I do wrong?”
”Where could I have screwed up?”
”Assuming I did not screw up – what else could have gone wrong?”
Having answered all those questions you try again. Addressing as many variables that could have gone wrong.
Once again in front of the machine… hoping… dreading… ”DAMN IT! Nothing again” Disappointment washes over you.
”What didn’t i think of before?”
”What else could be the matter?”
You think. You ask around, the opinions of people more clever than you… seeing reasons and solutions.
”Well lets go again!” you think.
Albert Einstein’s quote ”Insanity: doing the same thing over and over again and expecting different results.” might pass through you mind but you ignore it. For your own sanity’s sake.
Deep breath, and lets start again. Changing more things. Addressing new variables that might affect your results. Step by step you follow through the motions again. You reach the control step. Heart beating… despairing and hopeful at the same time. Dare I look? Dare I not look at the plot forming in front of my eyes?
And this is the point where you start praying… as I wrote on Friday in my facebook status ”Praying to all possible deities, pagan pantheons and other gods alike… please work…. pleaaase work…”
The sigh of relief and the happy smile of seeing something resembling results on your plot makes you look like a lunatic. In that instant all the disappointment of all the previous failures vanishes and the world is good!